Six people have been killed in an attack in central London in which three assailants were shot dead by police, Scotland Yard has said.
A white van hit several pedestrians on London Bridge just after 22:00 BST.
Three men then left the vehicle and stabbed a number of people in Borough Market, south of the bridge, an area known for its restaurants and bars.
Armed officers confronted and shot three male suspects within eight minutes.
London Ambulance Service said at least 30 people have been taken to hospital.
Metropolitan Police Assistant Commissioner Mark Rowley said: “The suspects were wearing what looked like explosive vests but these were later established to be hoaxes.”
He said it was currently believed there were only three attackers involved.
The British Transport Police said one of its officers was seriously injured after being stabbed as he responded to the incident, but his condition was not said to be life-threatening.
Prime Minister Theresa May described the incidents as “dreadful events” and will chair a meeting of the government’s Cobra emergency committee on Sunday.
London Mayor Sadiq Khan called it “a deliberate and cowardly attack on innocent Londoners”.
Eyewitnesses told BBC home affairs correspondent Tom Symonds they saw people getting out of the van after the attack on the bridge and running towards Borough Market.
Gunshots were later heard in the area while one social media user posted a photograph appearing to show one of the attackers lying on the ground outside a pub in the food market, with what police now say is a fake bomb vest strapped to his body.
‘Van hit five people’
The BBC’s Tom Symonds said a security guard who oversees a number of pubs in the London Bridge area said he saw four people stabbed by three attackers.
BBC reporter Holly Jones, who was on the bridge at the time of the attack, said a van driven by a man was “probably travelling at about 50 miles an hour” before it hit a number of people.
“He swerved right round me and then hit about five or six people. He hit about two people in front of me and then three behind,” Ms Jones told the BBC News Channel.
Five or six people were being treated for injuries after the vehicle mounted the pavement and hit them, she said.
“I’d say there are about four severely injured people. They all have paramedics assisting them at the moment.”
She said the van came from the direction of central London and headed towards the south side of the river.
She said a French woman was among the injured. She had said she did not know where two people she had been with were.
Speaking to the Press Association, Will Orton described being in a pub in the area and seeing people coming running inside.
“We didn’t really know what was going on,” he said.
“We thought maybe there was a fight or something outside. And then there were almost hundreds of people coming inside.
“The bouncers did a really good job, they shut the doors and locked everyone in. There was panic – it seemed like it was literally outside the door. People were coming inside and saying they had witnessed people being stabbed.”
The attack comes almost two weeks after 22 people died in a suicide bombing at a concert in Manchester. In March, five people died in London when a car was driven at pedestrians on Westminster Bridge and a police officer was stabbed outside Parliament.
On Twitter, Labour Party leader Jeremy Corbyn described the incidents as “brutal and shocking”.
Transport for London (TfL) said London Bridge had been closed in both directions, while neighbouring Southwark Bridge has also been shut.
TfL said there were further closures in Borough High Street, while on the north side of the river, road closures included Lower Thames Street and part of Cannon Street.
The Met Police has set up a casualty bureau on 0800 096 1233 and 020 7158 0197 for people concerned about friends or relatives who may be affected.
Facebook has activated its safety check so people in London could post a message to let friends and relatives know they were safe.